What You Need to Know About Estrogen Blockers for Men

Different Types of Estrogen Blockers for Men

There are several types of estrogen blockers for men. Some estrogen blockers work by blocking the production of estrogen, while others block the effects of estrogen once it’s been produced. Androgens like testosterone are converted into estrogen within cells. So, by blocking this conversion process, these medications effectively reduce the formation of estrogen in men.

The most commonly prescribed type of estrogen blockers is Enjuvia. Enjuvia functions as an aromatase inhibitor, targeting the enzyme responsible for converting testosterone into estrogen. Aromatase inhibitors are usually taken orally. They’re effective for treating breast cancer, prostate cancer, and endometriosis.

Another type of estrogen blocker for men is Femara. It works by blocking the action of estrogen receptors, thus stopping the body from responding to estrogen. This type of estrogen blocker is utilized in the treatment of various conditions, including breast cancer, ovarian cancer, uterine fibroids, polycystic ovary syndrome, and endometrioma.

What Are The Symptoms of Estrogen and Testosterone Imbalance?

Estrogen dominance symptoms typically begin during puberty and are often associated with PMS and menopause. These include hot flashes, mood swings, fatigue, irritability, depression, anxiety, insomnia, bloating, breast tenderness, vaginal dryness, headaches, heart palpitations, joint pain, acne, hair loss, weight gain, and even cancer.

Excess aromatase enzyme activity can lead to a condition known as excess aromatase syndrome. This syndrome results in elevated estradiol levels, increasing the risk of cardiovascular disease, osteoporosis, diabetes, and certain cancers.

Treatment includes reducing circulating estrogens through medications such as birth control pills, selective estrogen receptor modulators (SERMs), antiandrogens, and aromatase inhibitors.

Benefits of Estrogen Blockers in Men

Prostate cancer patients often take estrogen blockers to prevent bone loss. Moreover, there is emerging evidence suggesting that estrogen blockers could play a role in reducing the risk of cardiovascular diseases. Researchers looked at data from nearly 40,000 male participants in the Health Professionals Follow-up Study. Men who took estrogen blockers had a 41% lower risk of developing coronary artery disease compared to those who did not use the drugs.

When to Talk to Your Provider about Estrogen Blockers

Talk to your provider at XSculpt about getting tested if you notice symptoms such as decreased libido or erectile dysfunction. Although some providers offer saliva tests, hormone testing is generally done through blood work. There are several types of hormone testing, including those that measure testosterone levels and those that look at the hormones associated with fertility.

Treatment options include prescription medications, lifestyle changes, or surgical intervention.

Learn more about the role and effectiveness of estrogen blockers for men with gynecomastia here.